Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 3/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684705 | 0.99 | MEN1 (0.48) | MEN1KMT2ACNR1CNR2ACACB | |
| SCHEMBL10677816 | 0.98 | MEN1 (0.49) | MEN1KMT2ACNR1CNR2ACACB | |
| SCHEMBL10682289 | 0.98 | MEN1 (0.49) | MEN1KMT2ACNR1CNR2ACACB | |
| SCHEMBL10682241 | 0.97 | MEN1 (0.48) | MEN1KMT2ACNR1CNR2ACACB | |
| SCHEMBL10684106 | 0.96 | MEN1 (0.49) | MEN1KMT2ACNR1CNR2ACACB | |
| SCHEMBL10683532 | 0.95 | MEN1 (0.47) | MEN1KMT2ACNR1CNR2ACACB | |
| SCHEMBL10681788 | 0.92 | MEN1 (0.46) | MEN1KMT2ACNR1CNR2ACACB | |
| SCHEMBL10683635 | 0.88 | MEN1 (0.58) | MEN1KMT2AACACBKDM4CNPC1 | |
| SCHEMBL10684274 | 0.87 | MEN1 (0.57) | MEN1KMT2AACACBFKBP1AKDM4C | |
| SCHEMBL10679023 | 0.86 | MEN1 (0.58) | MEN1KMT2AACACBFKBP1AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761420-A | CARDIOVASCULAR DISORDERS | LABORATOIRES SYNTEX S.A. (FR) | 1988-08-02 | — | — | US | disclosed |
| EP-0249245-A2 | Antihypertensive dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1987-12-16 | — | — | EP | disclosed |