Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10677002 | 0.99 | EPHX2 (0.58) | EPHX2LMNAHPGDNPC1POLB | |
| SCHEMBL16222307 | 0.89 | EPHX2 (0.66) | EPHX2LMNAHPGDPOLBNAMPT | |
| SCHEMBL10676261 | 0.86 | EPHX2 (0.47) | EPHX2LMNAHPGDNAMPTMEN1 | |
| Hydrochloric Acid SCHEMBL10678742 | 0.86 | EPHX2 (0.61) | EPHX2LMNAHPGDPRSS1ACR | |
| SCHEMBL27694063 | 0.86 | EPHX2 (0.45) | EPHX2LMNANAMPTPRSS1ALDH1A1 | |
| SCHEMBL10684701 | 0.85 | EPHX2 (0.52) | EPHX2LMNAHPGDNAMPTMEN1 | |
| Hydrochloric Acid SCHEMBL10766698 | 0.85 | EPHX2 (0.47) | EPHX2LMNAHPGDNAMPTMEN1 | |
| Hydrochloric Acid SCHEMBL10688921 | 0.85 | EPHX2 (0.44) | EPHX2LMNANAMPTPRSS1ACR | |
| SCHEMBL10687581 | 0.85 | MEN1 (0.46) | EPHX2LMNAHPGDPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL10680333 | 0.85 | EPHX2 (0.49) | EPHX2HPGDPRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746737-A | ANTI-TRYPSIN, ANTI-THROMBIN AGENTS, ANTICOAGULANTS | KOWA CO., LTD. (JP) | 1988-05-24 | — | — | US | claimed |