Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 5/20 | 0.42 |
| ▸ | GSK3B | P49841 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10510270 | 0.93 | KDM4E (0.48) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL10369147 | 0.92 | KCNH2 (0.49) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL10684793 | 0.90 | KCNH2 (0.51) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL10679368 | 0.87 | KCNH2 (0.37) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8385037 | 0.86 | KCNH2 (0.64) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL10509748 | 0.86 | KDM4E (0.49) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9688244 | 0.85 | KCNH2 (0.47) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| Hydrochloric Acid SCHEMBL10368756 | 0.85 | KCNH2 (0.63) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9689834 | 0.84 | KCNH2 (0.47) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9687744 | 0.84 | KCNH2 (0.47) | KCNH2CACNA1FPOLBMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284935-A1 | 5-Substituted quinolone- and naphthyridone carboxylic acid derivatives | BAYER AG (DE) | 1988-10-05 | — | — | EP | claimed |
| EP-0284935-A1 | 5-Substituted quinolone- and naphthyridone carboxylic acid derivatives | BAYER AG (DE) | 1988-10-05 | — | — | EP | disclosed |