Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10676254 | 0.89 | MAPK1 (0.67) | MAPK1GAARXFP1NPSR1KDM4E | |
| Water SCHEMBL10680272 | 0.89 | MAPK1 (0.53) | MAPK1GAARXFP1NPSR1KDM4E | |
| SCHEMBL10607926 | 0.88 | KDM4E (0.72) | MAPK1GAARXFP1NPSR1KDM4E | |
| SCHEMBL10673454 | 0.88 | MAPT (0.66) | MAPK1GAARXFP1NPSR1KDM4E | |
| SCHEMBL10679109 | 0.87 | MAPT (0.67) | MAPK1GAANPSR1KDM4EMEN1 | |
| SCHEMBL10670514 | 0.86 | KDM4E (0.54) | MAPK1GAARXFP1NPSR1KDM4E | |
| SCHEMBL10678542 | 0.85 | KMT2A (0.67) | MAPK1GAARXFP1NPSR1KDM4E | |
| SCHEMBL10670455 | 0.85 | PDE5A (0.60) | MAPK1GAARXFP1NPSR1KDM4E | |
| SCHEMBL531233 | 0.85 | MAPK1 (0.81) | MAPK1GAARXFP1NPSR1KDM4E | |
| SCHEMBL10673183 | 0.85 | KDM4E (0.52) | MAPK1GAARXFP1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788188-A | ANTICONVULSANTS, SEDATIVES, ANXIOLYTIC AGENTS | SANOFI (S.A.) (FR) | 1988-11-29 | — | — | US | disclosed |