Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685217 | 0.92 | ESR2 (0.44) | ESR2ESR1KMT2AMEN1HSD17B10 | |
| SCHEMBL10683433 | 0.90 | KLK7 (0.44) | ESR2ESR1KMT2AMEN1POLB | |
| SCHEMBL10680693 | 0.88 | ESR2 (0.47) | ESR2ESR1KMT2AMEN1KLK7 | |
| SCHEMBL10680616 | 0.87 | ESR1 (0.38) | ESR2ESR1KMT2AMEN1HSD17B10 | |
| SCHEMBL10679719 | 0.86 | ESR2 (0.46) | ESR2ESR1KMT2AMEN1HSD17B10 | |
| SCHEMBL1888816 | 0.86 | MEN1 (0.51) | ESR2ESR1KMT2AMEN1HSD17B10 | |
| SCHEMBL6572282 | 0.86 | MEN1 (0.51) | ESR2ESR1KMT2AMEN1HSD17B10 | |
| SCHEMBL7786792 | 0.85 | ESR2 (0.45) | ESR2ESR1KMT2AMEN1HSD17B10 | |
| Potassium SCHEMBL10738982 | 0.85 | MEN1 (0.50) | ESR2ESR1KMT2AMEN1HSD17B10 | |
| SCHEMBL10738974 | 0.85 | MEN1 (0.50) | ESR2ESR1KMT2AMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782073-A | BRAIN EDEMA | MERCK & CO., INC. (US) | 1988-11-01 | — | — | US | disclosed |