⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489220 | 1.00 | — | — | |
| SCHEMBL8977443 | 0.83 | — | — | |
| SCHEMBL17744991 | 0.81 | CA1 (0.36) | — | |
| SCHEMBL6311729 | 0.71 | — | — | |
| SCHEMBL2355120 | 0.69 | — | — | |
| SCHEMBL14763939 | 0.69 | — | — | |
| SCHEMBL2034698 | 0.65 | — | — | |
| SCHEMBL16320122 | 0.65 | — | — | |
| SCHEMBL511158 | 0.65 | — | — | |
| SCHEMBL1094690 | 0.64 | CYP19A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4730065-A | BRONCHODILATORS, HYPOTENSIVES, ANTISECRETORY | AMERICAN CYANAMID COMPANY (US) | 1988-03-08 | — | — | US | disclosed |
| US-4518790-A | 15-Deoxy-16-hydroxy-16-vinyl and cyclopropyl substituted prostanoic acids and congeners | AMERICAN CYANAMID COMPANY (US) | 1985-05-21 | — | — | US | disclosed |
| US-4504417-A | 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners | AMERICAN CYANAMID COMPANY (US) | 1985-03-12 | — | — | US | disclosed |
| US-4429148-A | PROSTAGLANDINS; BRONCHODILATORS, HYPTOTENSIVES | AMERICAN CYANAMID COMPANY (US) | 1984-01-31 | — | — | US | disclosed |
| US-4390711-A | 16-Hydroxy-5-iodo-prostacyclin analogs of the 1 series | AMERICAN CYANAMID COMPANY (US) | 1983-06-28 | — | — | US | disclosed |
| US-4358605-A | BRONCHODILATORS, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1982-11-09 | — | — | US | disclosed |
| EP-0052204-A1 | Prostacyclin analogs of the 1 series and related analogs | AMERICAN CYANAMID COMPANY (US) | 1982-05-26 | — | — | EP | disclosed |
| US-4328358-A | ENANTIOMORPHS USEFUL AS BRONCHODILATORS, HYPOTENSIVE AGENTS OR GASTRIC ANTISECRETORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1982-05-04 | — | — | US | disclosed |
| US-4321405-A | HYPOTENSIVE AGENTS, BRONCHODILATORS, ANTISECRETORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1982-03-23 | — | — | US | disclosed |
| US-4299988-A | TREATMENT OF HIGH BLOOD PRESSURE AND MUSCULAR DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1981-11-10 | — | — | US | disclosed |
| US-4131737-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4113967-A | BRONCHODILATORS, HYPOTENSIVE, ANTISECRETORY | AMERICAN CYANAMID COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-4111959-A | BRONCHODILATORS, ANTIINFLAMMATORY, HYPOTENSIVE, ANTISECRETORY | AMERICAN CYANAMID COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4107441-A | HYPOTENSIVE, ANTIULCER, BRONCHODILATORS, ANTIMICROBIAL, ANTICONVULSANTS | AMERICAN CYANAMID COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-4076947-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4061672-A | Derivatives of 9-hydroxy-13-trans-prostenoic acid | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-4061670-A | BRONCHODILATOR, HYPOTENSIVE, ANTISECRETORY | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-RE29469-E | PROSTAGLANDINS; BRONCHODILATORS, HYPOTENSIVES, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-11-08 | — | — | US | disclosed |
| US-4028396-A | BRONCHODILATORS, GASTRIC ACID SECRETION INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-3950406-A | BRONCHODILATORS, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1976-04-13 | — | — | US | disclosed |