Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 13/20 | 0.38 |
| ▸ | CA2 | P00918 | 13/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10678808 | 0.88 | MEN1 (0.46) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10659444 | 0.88 | MEN1 (0.46) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10682987 | 0.88 | MEN1 (0.46) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10546306 | 0.78 | MEN1 (0.44) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10544823 | 0.78 | MEN1 (0.45) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10931389 | 0.77 | MEN1 (0.43) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10681307 | 0.77 | MEN1 (0.38) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10680470 | 0.77 | MEN1 (0.38) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10678695 | 0.76 | MEN1 (0.42) | MEN1KMT2ACCKBRLMNACA1 | |
| SCHEMBL10547045 | 0.76 | MEN1 (0.42) | MEN1KMT2ACCKBRLMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775670-A | BACTERICIDES, ANTIBIOTICS | E. R. SQUIBB & SONS, INC. (US) | 1988-10-04 | — | — | US | disclosed |
| EP-0187355-A1 | Process for preparing beta-lactam antibiotics | E.R. Squibb & Sons, Inc. (US) | 1986-07-16 | — | — | EP | disclosed |