Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 12/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | NAPEPLD | Q6IQ20 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675281 | 0.90 | SMN1; SMN2 (0.48) | PIK3CBHTTMEN1KMT2APOLB | |
| SCHEMBL10678093 | 0.84 | AKT1 (0.47) | PIK3CATSHRMEN1KMT2ANPSR1 | |
| SCHEMBL10680533 | 0.82 | ADORA2A (0.43) | PIK3CBPIK3CAMEN1KMT2AMAPT | |
| SCHEMBL10676266 | 0.81 | ADORA2A (0.47) | PIK3CBPIK3CAMEN1KMT2ALMNA | |
| Water SCHEMBL10675127 | 0.79 | ADORA2A (0.46) | PIK3CBPIK3CAPKMHTTMEN1 | |
| SCHEMBL10681243 | 0.78 | ADORA2A (0.44) | PIK3CBPIK3CAMEN1KMT2APOLB | |
| SCHEMBL821715 | 0.76 | NPC1 (0.69) | PIK3CBPIK3CAPKMHTTLMNA | |
| SCHEMBL10677336 | 0.74 | NPC1 (0.47) | PKMKMT2ALMNAMAPTNPC1 | |
| SCHEMBL10674326 | 0.73 | NPC1 (0.46) | HTTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL10673150 | 0.72 | GRIN2D (0.46) | POLBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4729995-A | ANTIALLERGENS | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1988-03-08 | — | — | US | disclosed |
| EP-0243817-A1 | Novel pyrimidine compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1987-11-04 | — | — | EP | disclosed |