Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | CSK | P41240 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690922 | 0.88 | DHODH (0.49) | PARP1KDM4EKMT2ADHODHNPC1 | |
| SCHEMBL10683980 | 0.85 | KDM4E (0.46) | PARP1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL10688446 | 0.84 | DHODH (0.54) | PARP1KDM4EKMT2ADHODHNPC1 | |
| SCHEMBL10687218 | 0.83 | DHODH (0.48) | PARP1KDM4EKMT2ADHODHSMN1; SMN2 | |
| SCHEMBL10687978 | 0.82 | PARP1 (0.59) | PARP1KDM4EKMT2ADHODHSMN1; SMN2 | |
| SCHEMBL10685982 | 0.82 | PARP1 (0.54) | PARP1KDM4EPOLBKMT2ADHODH | |
| Phosphoric Acid SCHEMBL10686961 | 0.80 | DHODH (0.45) | PARP1KDM4EKMT2ADHODHSMN1; SMN2 | |
| Phosphoric Acid SCHEMBL10681463 | 0.79 | MEN1 (0.51) | PARP1KDM4EPOLBKMT2ADHODH | |
| SCHEMBL10688291 | 0.78 | DHODH (0.47) | PARP1KDM4EPOLBKMT2ADHODH | |
| SCHEMBL10687494 | 0.76 | DHODH (0.50) | PARP1KDM4EPOLBKMT2ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769384-A | ANTIULCER AGENTS | NIPPON SHINYAKU CO. LTD. (JP) | 1988-09-06 | — | — | US | disclosed |