SCHEMBL10685237

SCHEMBL10685237

Fc1c(F)c(F)c(CCI)c(CCI)c1F

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
CASP1 P29466 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7331916 0.93 SLC6A2 (0.31) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL7197249 0.75
SCHEMBL6669767 0.72
SCHEMBL8672544 0.70 SLC6A2 (0.36)
SCHEMBL13258720 0.65 SLC6A2 (0.33)
SCHEMBL206669 0.65
SCHEMBL13804362 0.62 IDH1 (0.32)
SCHEMBL24063638 0.62 SLC6A2 (0.37)
SCHEMBL5327960 0.60 SMN1; SMN2 (0.33)
SCHEMBL3113744 0.60 SLC6A2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4774302-A BROMINE, IODINE CONTAINING AROMATIC CATALYSTS NIPPON MEKTRON LIMITED (JP) 1988-09-27 US claimed