Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 10/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279521 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP2C19BLMPMP22KDM4E | |
| SCHEMBL5182652 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP2C19BLMPMP22KDM4E | |
| SCHEMBL5182245 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP2C19BLMPMP22KDM4E | |
| SCHEMBL31563007 | 0.83 | GRM2 (0.58) | GRM2GRM3CYP1A2CYP2C19BLM | |
| SCHEMBL27748006 | 0.82 | GRM2 (0.51) | GRM2GRM3CYP1A2CYP2C19BLM | |
| SCHEMBL202819 | 0.82 | GRM2 (0.51) | GRM2GRM3CYP1A2CYP2C19BLM | |
| SCHEMBL3616371 | 0.82 | GRM2 (0.51) | GRM2GRM3CYP1A2CYP2C19BLM | |
| SCHEMBL8241245 | 0.82 | TAAR1 (0.49) | GRM2GRM3CYP1A2CYP2C19BLM | |
| Hydrochloric Acid SCHEMBL1807415 | 0.80 | GRM2 (0.50) | GRM2GRM3CYP1A2CYP2C19BLM | |
| Hydrochloric Acid SCHEMBL31587976 | 0.80 | GRM2 (0.50) | GRM2GRM3CYP1A2CYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |