Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 16/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680718 | 0.91 | POLB (0.54) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10681758 | 0.91 | CACNA1F (0.52) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10682682 | 0.91 | KCNH2 (0.52) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10679869 | 0.90 | MEN1 (0.53) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10679828 | 0.89 | KCNH2 (0.50) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10680080 | 0.89 | CACNA1F (0.50) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10684659 | 0.88 | KCNH2 (0.53) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9372414 | 0.88 | KCNH2 (0.53) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10443389 | 0.88 | KCNH2 (0.53) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10679566 | 0.88 | KCNH2 (0.57) | CACNA1FPOLBMAPK1CACNA1DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284935-A1 | 5-Substituted quinolone- and naphthyridone carboxylic acid derivatives | BAYER AG (DE) | 1988-10-05 | — | — | EP | disclosed |