Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684860 | 0.90 | PARP1 (0.46) | KDM4EALDH1A1PARP1DHODHHPGD | |
| SCHEMBL10688473 | 0.89 | AKR1C2 (0.46) | KDM4EALDH1A1PARP1DHODHHPGD | |
| SCHEMBL10686912 | 0.88 | DHODH (0.48) | KDM4EALDH1A1PARP1DHODHHPGD | |
| SCHEMBL10689910 | 0.88 | PARP1 (0.45) | KDM4EALDH1A1PARP1DHODHHPGD | |
| SCHEMBL10690859 | 0.87 | DHODH (0.52) | KDM4EALDH1A1PARP1DHODHHPGD | |
| SCHEMBL10687590 | 0.87 | DHODH (0.52) | KDM4EALDH1A1PARP1DHODHHPGD | |
| Sulfuric Acid SCHEMBL10687272 | 0.86 | DHODH (0.49) | KDM4EALDH1A1PARP1DHODHHPGD | |
| Hydrochloric Acid SCHEMBL10692537 | 0.86 | DHODH (0.51) | KDM4EALDH1A1PARP1DHODHHPGD | |
| Bromide SCHEMBL10687725 | 0.86 | DHODH (0.51) | KDM4EALDH1A1PARP1DHODHHPGD | |
| SCHEMBL10684850 | 0.85 | DHODH (0.48) | KDM4EALDH1A1PARP1DHODHHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769384-A | ANTIULCER AGENTS | NIPPON SHINYAKU CO. LTD. (JP) | 1988-09-06 | — | — | US | disclosed |