Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688991 | 1.00 | TDP1 (0.52) | TDP1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL11331176 | 0.82 | TDP1 (0.50) | TDP1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL3605648 | 0.82 | TDP1 (0.50) | TDP1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL29528455 | 0.82 | TDP1 (0.50) | TDP1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL2093129 | 0.82 | TDP1 (0.55) | TDP1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL256703 | 0.82 | TDP1 (0.50) | TDP1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL10323624 | 0.82 | TDP1 (0.50) | TDP1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL3605644 | 0.82 | TDP1 (0.50) | TDP1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL2093131 | 0.82 | TDP1 (0.55) | TDP1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL1569641 | 0.82 | TDP1 (0.50) | TDP1MAPTALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103130663-B | Cinnamylate ester compound and application thereof | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2014-06-18 | — | — | CN | disclosed |
| CN-103130663-A | Cinnamylate ester compound and application thereof | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2013-06-05 | — | — | CN | disclosed |
| US-4742062-A | Benzylpiperazine compound and pharmaceutical composition as hypolipidemic agent | KANEBO, LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0209843-A2 | Benzylpiperazine compound, preparation thereof, pharmaceutical composition, and use | KANEBO, LTD. (JP) | 1987-01-28 | — | — | EP | disclosed |
| US-4431815-A | CARDIOTONIC AND ANTISHOCK AGENTS; ANTICOAGULANTS | BURROUGHS WELLCOME CO. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4425354-A | CARDIOVASCULAR DISORDERS | BURROUGHS WELLCOME CO. (US) | 1984-01-10 | — | — | US | disclosed |
| EP-0003732-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-10-19 | — | — | EP | disclosed |
| US-4405634-A | Imidazole derivatives for treating myocardial infarction | BURROUGHS WELLCOME CO. (US) | 1983-09-20 | — | — | US | disclosed |
| US-4396771-A | THROMBOEMBOLIC DISORDERS, SHOCK | BURROUGHS WELLCOME CO. (US) | 1983-08-02 | — | — | US | disclosed |
| US-4357340-A | Imidazole derivatives and angina pectoris | BURROUGHS WELLCOME CO. (US) | 1982-11-02 | — | — | US | disclosed |
| EP-0003732-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-09-05 | — | — | EP | disclosed |
| US-4017631-A | MICROBIOCIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-04-12 | — | — | US | disclosed |
| US-3991202-A | ANTIMICROBIALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-09 | — | — | US | disclosed |