Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | TTR | P02766 | 1/20 | 0.63 |
| ▸ | PPOX | P50336 | 1/20 | 0.63 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5933816 | 0.92 | MEN1 (0.74) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL30088466 | 0.92 | MEN1 (0.74) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL10688162 | 0.89 | TDP1 (0.72) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL38860 | 0.86 | MEN1 (0.68) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL10685102 | 0.86 | TDP1 (0.84) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL10536730 | 0.85 | MEN1 (0.67) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL10786523 | 0.85 | TDP1 (0.62) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL9852597 | 0.85 | TDP1 (0.78) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL11062686 | 0.84 | MEN1 (0.66) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL10686499 | 0.84 | TDP1 (0.52) | KMT2AMEN1TDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743703-A | Herbicidal 4-fluoroalkyl-4'-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1988-05-10 | — | — | US | disclosed |