Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.89 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6127516 | 0.88 | CYP2D6 (0.82) | TSHRCYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6127693 | 0.88 | CYP2D6 (0.82) | TSHRCYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6122455 | 0.86 | TSHR (0.70) | TSHRCYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL28820376 | 0.81 | USP2 (0.67) | TSHRCYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL27601052 | 0.81 | CYP2D6 (0.70) | TSHRCYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6123283 | 0.80 | TSHR (0.58) | TSHRCYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL23052533 | 0.79 | CYP2D6 (0.72) | TSHRCYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL20211031 | 0.79 | CYP2D6 (0.72) | TSHRCYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL10154071 | 0.79 | TSHR (0.72) | TSHRCYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL12465590 | 0.79 | TSHR (0.68) | TSHRCYP2D6CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761430-A | ANTILIPEMIC AGENTS | DROPIC, SOCIETE CIVILE DE GESTION DE DROITS DE PROPRIETE INDUSTRIELLE (FR) | 1988-08-02 | — | — | US | disclosed |
| US-4613618-A | VEGETABLE OILS, VASODILATORS | CHOAY S.A. (FR) | 1986-09-23 | — | — | US | disclosed |