SCHEMBL10690214

SCHEMBL10690214

FC(F)(F)c1ccc(Oc2ccc(Br)c(CSCc3ccc(Cl)cc3)c2)c(Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 6/20 0.47
SLC6A4 P31645 6/20 0.45
HTR2A P28223 5/20 0.45
KCNH2 Q12809 5/20 0.45
MEN1 O00255 1/20 0.40
TTR P02766 1/20 0.40
PPOX P50336 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MRGPRX4 Q96LA9 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10482233 0.81 FFAR1 (0.50) FFAR1SLC6A4HTR2AKCNH2MEN1
SCHEMBL10969104 0.76 FFAR1 (0.60) FFAR1SLC6A4HTR2AKCNH2MEN1
SCHEMBL10516125 0.74 FFAR1 (0.70) FFAR1SLC6A4HTR2AKCNH2MEN1
SCHEMBL10797339 0.74 FFAR1 (0.47) FFAR1SLC6A4HTR2AKCNH2MEN1
SCHEMBL11436072 0.73 FFAR1 (0.52) FFAR1SLC6A4HTR2AKCNH2MEN1
SCHEMBL10482200 0.73 FFAR1 (0.49) FFAR1SLC6A4HTR2AKCNH2MEN1
SCHEMBL10482098 0.73 SLC6A4 (0.53) FFAR1SLC6A4HTR2AKCNH2MEN1
SCHEMBL10797331 0.72 FFAR1 (0.45) FFAR1SLC6A4HTR2AKCNH2MEN1
SCHEMBL9694760 0.72 FFAR1 (0.51) FFAR1SLC6A4HTR2AKCNH2MEN1
SCHEMBL10691494 0.72 FFAR1 (0.49) FFAR1SLC6A4HTR2AKCNH2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4744812-A HALOGENATED DIPHENYL ETHER BASF AKTIENGESELLSCHAFT (DE) 1988-05-17 US disclosed