Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.36 |
| ▸ | REN | P00797 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691717 | 0.85 | AR (0.32) | — | |
| SCHEMBL28529472 | 0.78 | ACE (0.36) | ACERENKDM4EF2LMNA | |
| SCHEMBL4312891 | 0.77 | ACE (0.46) | ACERENKDM4EF2LMNA | |
| SCHEMBL3094568 | 0.76 | ACE (0.45) | ACERENKDM4EF2LMNA | |
| SCHEMBL3093621 | 0.76 | ACE (0.45) | ACERENKDM4EF2LMNA | |
| Hydrochloric Acid SCHEMBL10694558 | 0.75 | ACE (0.45) | ACERENKDM4EF2LMNA | |
| SCHEMBL7207958 | 0.74 | ACE (0.44) | ACERENKDM4EF2LMNA | |
| SCHEMBL3803835 | 0.74 | ACE (0.44) | ACERENKDM4EF2LMNA | |
| SCHEMBL1432340 | 0.72 | ACE (0.49) | ACERENKDM4EF2LMNA | |
| SCHEMBL1881293 | 0.72 | ACE (0.49) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253785-A1 | Efficient stereoconservative syntheses of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines and intermediates therein | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1988-01-20 | — | — | EP | disclosed |