Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 11/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685670 | 0.74 | MAP3K5 (0.51) | MAP3K5NOTUMKEAP1MAPTNPC1 | |
| SCHEMBL15091190 | 0.74 | MAP3K5 (0.51) | MAP3K5NOTUMKEAP1MAPTNPC1 | |
| SCHEMBL24405876 | 0.74 | MAP3K5 (0.48) | MAP3K5NOTUMKEAP1MAPTNPC1 | |
| SCHEMBL3510845 | 0.74 | NOTUM (0.50) | MAP3K5NOTUMKEAP1KMT2A | |
| SCHEMBL10691319 | 0.74 | MAP3K5 (0.48) | MAP3K5NOTUMKEAP1MAPTNPC1 | |
| SCHEMBL10685640 | 0.73 | NOTUM (0.51) | MAP3K5NOTUMKEAP1MAPTNPC1 | |
| SCHEMBL28969422 | 0.70 | MEN1 (0.48) | MAP3K5NOTUMKEAP1RAB9ACYP19A1 | |
| SCHEMBL10694005 | 0.70 | NOTUM (0.50) | MAP3K5NOTUMKEAP1 | |
| SCHEMBL8779829 | 0.69 | CCR1 (0.39) | KEAP1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL15093948 | 0.68 | MAP3K5 (0.49) | MAP3K5NOTUMKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775762-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-10-04 | — | — | US | claimed |