Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 6/20 | 0.41 |
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678105 | 0.88 | SCN9A (0.47) | SCN9AACECTSSCTSKPTPN1 | |
| SCHEMBL26136049 | 0.87 | ACE (0.52) | SCN9AACECTSSCTSKPTPN1 | |
| SCHEMBL9222337 | 0.83 | PI4K2A (0.35) | ITGB3ITGA2BITGB1ITGAVITGA4 | |
| SCHEMBL29286180 | 0.78 | ACE (0.52) | SCN9AACECTSSCTSKPTPN1 | |
| SCHEMBL7859251 | 0.78 | ACE (0.52) | SCN9AACECTSSCTSKPTPN1 | |
| SCHEMBL29286179 | 0.78 | ACE (0.52) | SCN9AACECTSSCTSKPTPN1 | |
| SCHEMBL7859254 | 0.78 | ACE (0.52) | SCN9AACECTSSCTSKPTPN1 | |
| SCHEMBL23357002 | 0.77 | ACE (0.51) | SCN9AACECTSSCTSKPTPN1 | |
| SCHEMBL864799 | 0.77 | PTPN1 (0.54) | SCN9AACECTSSCTSKPTPN1 | |
| SCHEMBL864800 | 0.77 | PTPN1 (0.54) | SCN9AACECTSSCTSKPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4786591-A | HETEROGENEOUS IMMUNOASSAY | BOEHRINGER MANNHEIM GMBH (DE) | 1988-11-22 | — | — | US | disclosed |