Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27250762 | 0.81 | CA12 (0.51) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL22230138 | 0.80 | CA12 (0.50) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL2411328 | 0.80 | CA12 (0.50) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL25223687 | 0.80 | CA12 (0.50) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL4670546 | 0.79 | CA12 (0.65) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL29313354 | 0.76 | CA12 (0.47) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL27446396 | 0.76 | CA12 (0.47) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL27250759 | 0.76 | CA12 (0.49) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL14955293 | 0.75 | CA12 (0.51) | CA12CA1CA2CA9CYP3A4 | |
| SCHEMBL3832090 | 0.72 | CA12 (0.41) | CA12CA1CA2CA9CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255704-A2 | Pyridazinone derivatives, process for their preparation and their use as medicines | Roche Diagnostics GmbH (DE) | 1988-02-10 | — | — | EP | disclosed |