Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | PPOX | P50336 | 1/20 | 0.53 |
| ▸ | ESRRA | P11474 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bifenox SCHEMBL8541647 | 0.87 | TDP1 (1.00) | TDP1KMT2AMEN1TTRPPOX | |
| Bifenox SCHEMBL38816 | 0.87 | TDP1 (1.00) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11276396 | 0.87 | TDP1 (0.83) | TDP1KMT2AMEN1TTRPPOX | |
| Bifenox SCHEMBL30862569 | 0.87 | TDP1 (1.00) | TDP1KMT2AMEN1TTRPPOX | |
| Bifenox SCHEMBL28419037 | 0.86 | TDP1 (0.98) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10789320 | 0.86 | TDP1 (0.81) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10786433 | 0.85 | TDP1 (0.79) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10792602 | 0.85 | TDP1 (0.78) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL87462 | 0.84 | TDP1 (0.77) | TDP1KMT2AMEN1TTRPPOX | |
| Acifluorfen-Methyl SCHEMBL39092 | 0.83 | MEN1 (0.78) | TDP1KMT2AMEN1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743703-A | Herbicidal 4-fluoroalkyl-4'-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1988-05-10 | — | — | US | disclosed |