Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 15/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 15/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691798 | 0.91 | CYSLTR2 (0.50) | PPARGPPARACYSLTR2CYSLTR1LMNA | |
| SCHEMBL11027106 | 0.88 | CYSLTR2 (0.46) | PPARGPPARACYSLTR2CYSLTR1LMNA | |
| SCHEMBL10687332 | 0.87 | PPARG (0.46) | PPARGPPARACYSLTR2CYSLTR1LMNA | |
| SCHEMBL9377031 | 0.80 | MAOB (0.40) | PPARGPPARACYSLTR2CYSLTR1LMNA | |
| SCHEMBL10813199 | 0.79 | CYSLTR2 (0.58) | PPARGPPARACYSLTR2CYSLTR1LMNA | |
| SCHEMBL4343526 | 0.77 | PPARG (0.67) | PPARGPPARACYSLTR2CYSLTR1LMNA | |
| SCHEMBL10689737 | 0.77 | CYSLTR2 (0.80) | PPARGPPARACYSLTR2CYSLTR1LMNA | |
| SCHEMBL10690373 | 0.77 | MEN1 (0.53) | PPARGPPARACYSLTR2CYSLTR1LMNA | |
| SCHEMBL10955565 | 0.76 | CYSLTR2 (0.74) | PPARGPPARACYSLTR2CYSLTR1LMNA | |
| SCHEMBL10743664 | 0.75 | PPARG (0.54) | PPARGPPARACYSLTR2CYSLTR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782176-A | ANTIALLERGY | HOFFMANN-LA ROCHE INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0079637-B1 | ANTI-SRS-A CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION, AND PHARMACEUTICAL FORMULATION CONTAINING THEM | FISONS plc (GB) | 1987-01-28 | — | — | EP | disclosed |
| EP-0061800-B1 | ANTI SRS-A CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | FISONS plc (GB) | 1985-08-28 | — | — | EP | disclosed |
| US-4518612-A | Naphthalene and 2-oxo-benzopyran acids and derivatives and pharamaceutical use thereof | FISONS PLC (GB) | 1985-05-21 | — | — | US | disclosed |
| US-4507498-A | Phenoxycarboxylic acids | HOFFMANN-LA ROCHE INC. (US) | 1985-03-26 | — | — | US | disclosed |
| US-4474788-A | Anti-SRSA quinoline carboxylic acid derivatives | FISONS PLC (GB) | 1984-10-02 | — | — | US | disclosed |
| US-4424231-A | Compounds | FISONS LIMITED (GB) | 1984-01-03 | — | — | US | disclosed |
| EP-0079637-A1 | Anti-srs-a carboxylic acid derivatives, processes for their production, and pharmaceutical formulation containing them | FISONS plc (GB) | 1983-05-25 | — | — | EP | disclosed |
| EP-0061800-A1 | Anti SRS-A carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them | FISONS plc (GB) | 1982-10-06 | — | — | EP | disclosed |