Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 15/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 9/20 | 0.44 |
| ▸ | PLG | P00747 | 5/20 | 0.44 |
| ▸ | ADK | P55263 | 2/20 | 0.43 |
| ▸ | PROC | P04070 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116531 | 0.76 | F10 (0.62) | F10PRSS1F2PLGPROC | |
| SCHEMBL7116570 | 0.75 | F10 (0.56) | KMT2AF10PRSS1F2PLG | |
| SCHEMBL7125761 | 0.75 | F10 (0.71) | F10PRSS1F2PLGPROC | |
| SCHEMBL7122915 | 0.74 | F10 (0.58) | KMT2AF10PRSS1F2PLG | |
| SCHEMBL7122953 | 0.74 | F10 (0.58) | KMT2AF10ALDH1A1L3MBTL1ADK | |
| SCHEMBL7124635 | 0.73 | F10 (0.55) | KMT2AF10PRSS1F2PLG | |
| SCHEMBL7121510 | 0.73 | F10 (0.64) | KMT2AF10PRSS1F2PLG | |
| SCHEMBL7114475 | 0.73 | F10 (0.61) | F10PRSS1F2PLGPROC | |
| SCHEMBL7123929 | 0.72 | F10 (0.66) | KMT2AF10PRSS1F2PLG | |
| SCHEMBL7122745 | 0.71 | F10 (0.58) | KMT2AF10PRSS1ALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789675-A | HYPOTENSIVE, ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-06 | — | — | US | disclosed |
| EP-0233728-A1 | 1,4-Benzoxazine derivatives their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-08-26 | — | — | EP | disclosed |