Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.72 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HKDC1 | Q2TB90 | 4/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17987719 | 0.84 | TOP2A (1.00) | TOP2ASLC2A1HSP90AA1RAB9ASMN1; SMN2 | |
| SCHEMBL9321802 | 0.84 | TOP2A (1.00) | TOP2ASLC2A1HSP90AA1RAB9ASMN1; SMN2 | |
| SCHEMBL29883013 | 0.84 | TOP2A (1.00) | TOP2ASLC2A1HSP90AA1RAB9ASMN1; SMN2 | |
| SCHEMBL22056136 | 0.82 | TOP2A (0.76) | TOP2ASLC2A1HSP90AA1RAB9ASMN1; SMN2 | |
| SCHEMBL9320842 | 0.80 | TOP2A (0.72) | TOP2ASLC2A1HSP90AA1RAB9ASMN1; SMN2 | |
| SCHEMBL22056641 | 0.80 | HSP90AA1 (0.77) | TOP2ASLC2A1HSP90AA1RAB9ASMN1; SMN2 | |
| SCHEMBL22056829 | 0.80 | TOP2A (0.72) | TOP2ASLC2A1HSP90AA1RAB9ASMN1; SMN2 | |
| SCHEMBL9321797 | 0.80 | TOP2A (1.00) | TOP2ASLC2A1HSP90AA1RAB9ASMN1; SMN2 | |
| SCHEMBL9321789 | 0.80 | HSP90AA1 (0.77) | TOP2ASLC2A1HSP90AA1RAB9ASMN1; SMN2 | |
| SCHEMBL29882840 | 0.80 | TOP2A (0.72) | TOP2ASLC2A1HSP90AA1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719221-A | ANTIPROTOZOA AGENTS | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |