Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301483 | 1.00 | HRH3 (0.61) | HRH3ALDH1A1MAPTALOX15CYP1A2 | |
| SCHEMBL16599764 | 1.00 | HRH3 (0.61) | HRH3ALDH1A1MAPTALOX15CYP1A2 | |
| SCHEMBL7381713 | 1.00 | HRH3 (0.61) | HRH3ALDH1A1MAPTALOX15CYP1A2 | |
| SCHEMBL7293982 | 1.00 | HRH3 (0.61) | HRH3ALDH1A1MAPTALOX15CYP1A2 | |
| SCHEMBL7282658 | 1.00 | HRH3 (0.61) | HRH3ALDH1A1MAPTALOX15CYP1A2 | |
| SCHEMBL7294425 | 1.00 | HRH3 (0.61) | HRH3ALDH1A1MAPTALOX15CYP1A2 | |
| SCHEMBL7283494 | 0.98 | HRH3 (0.65) | HRH3ALDH1A1MAPTALOX15CYP1A2 | |
| SCHEMBL10695730 | 0.98 | HRH3 (0.65) | HRH3ALDH1A1MAPTALOX15CYP1A2 | |
| SCHEMBL7281286 | 0.98 | HRH3 (0.65) | HRH3ALDH1A1MAPTALOX15CYP1A2 | |
| SCHEMBL7293644 | 0.98 | HRH3 (0.65) | HRH3ALDH1A1MAPTALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |
| EP-0217372-A2 | Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |