Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16189696 | 0.80 | MAOB (0.45) | CA1CA9ALDH1A1ESR1ESR2 | |
| SCHEMBL28730829 | 0.80 | MAOB (0.45) | CA1CA9ALDH1A1ESR1ESR2 | |
| SCHEMBL28730848 | 0.77 | CYP2C9 (0.44) | SLC6A2SLC6A4SLC6A3CA1CA9 | |
| SCHEMBL28730824 | 0.77 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3CA1CA9 | |
| SCHEMBL28730845 | 0.77 | CYP2C9 (0.44) | SLC6A2SLC6A4SLC6A3CA1CA9 | |
| SCHEMBL8019731 | 0.77 | ESR2 (0.56) | ALDH1A1ESR1ESR2 | |
| SCHEMBL7261225 | 0.77 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3CA1CA9 | |
| SCHEMBL28730827 | 0.77 | MAOB (0.45) | CA1CA9 | |
| SCHEMBL639270 | 0.77 | MAOB (0.45) | CA1CA9 | |
| SCHEMBL639271 | 0.77 | MAOB (0.45) | CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251466-A2 | Chemical process for the preparation of esters of substituted cyclopropyl caboxylic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-07 | — | — | EP | disclosed |