SCHEMBL1069215

SCHEMBL1069215

Cc1c(NC(=O)c2cc3c(s2)CC(C)CC3)cccc1-c1cn(C)c(=O)c(Nc2ccc(N3CC[S+]([O-])CC3)cc2)n1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BTK Q06187 20/20 0.66
CD69 Q07108 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1069367 0.91 BTK (0.77) BTKCD69
SCHEMBL1065277 0.87 BTK (0.71) BTKCD69
SCHEMBL1069520 0.85 BTK (0.71) BTKCD69
SCHEMBL1068004 0.82 BTK (0.73) BTKCD69
SCHEMBL1065219 0.81 BTK (0.78) BTKCD69
SCHEMBL1068614 0.81 BTK (0.58) BTK
SCHEMBL1067929 0.81 BTK (0.69) BTKCD69
SCHEMBL1069516 0.81 BTK (0.72) BTK
SCHEMBL1070036 0.80 BTK (0.63) BTK
SCHEMBL13305728 0.79 BTK (1.00) BTKCD69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947835-B2 Certain substituted amides, method of making, and method of use thereof CGI PHARMACEUTICALS, INC. (US) 2011-05-24 US claimed
US-7947835-B2 Certain substituted amides, method of making, and method of use thereof CGI PHARMACEUTICALS, INC. (US) 2011-05-24 US disclosed
EP-2270200-A2 Kinase inhibitors, and methods of using and identifying kinase inhibitors CGI Pharmaceuticals, Inc. (US) 2011-01-05 EP disclosed