Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11177361 | 0.89 | POLB (0.46) | POLBHSP90AA1MEN1KMT2ATDP1 | |
| SCHEMBL10389840 | 0.87 | POLB (0.70) | POLBHSP90AA1MEN1KMT2ATDP1 | |
| SCHEMBL10723846 | 0.85 | HSP90AA1 (0.46) | POLBHSP90AA1MEN1KMT2ATDP1 | |
| SCHEMBL11359678 | 0.83 | POLB (0.46) | POLBHSP90AA1MEN1KMT2ATDP1 | |
| SCHEMBL10719659 | 0.82 | POLB (0.74) | POLBHSP90AA1MEN1KMT2ATDP1 | |
| SCHEMBL10390343 | 0.81 | POLB (0.57) | POLBHSP90AA1MEN1KMT2ATDP1 | |
| SCHEMBL11482530 | 0.81 | POLB (0.56) | POLBHSP90AA1MEN1KMT2ATDP1 | |
| SCHEMBL10576955 | 0.81 | POLB (0.56) | POLBHSP90AA1MEN1KMT2ATDP1 | |
| SCHEMBL11356833 | 0.81 | POLB (0.56) | POLBHSP90AA1MEN1KMT2ATDP1 | |
| SCHEMBL11291401 | 0.80 | POLB (0.55) | POLBHSP90AA1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258782-A2 | Use of 1-(substituted mercapto-hydroxyethyl)-triazoles in the treatment of illnesses | BAYER AG (DE) | 1988-03-09 | — | — | EP | disclosed |