Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 12/20 | 0.58 |
| ▸ | BCHE | P06276 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27804698 | 0.90 | BCHE (0.66) | KDM2BBCHE | |
| SCHEMBL13599987 | 0.89 | KDM2B (0.47) | KDM2BBCHESMN1; SMN2 | |
| SCHEMBL3842738 | 0.86 | SMN1; SMN2 (0.68) | KDM2BBCHESMN1; SMN2 | |
| SCHEMBL13149470 | 0.85 | BCHE (0.47) | KDM2BBCHESMN1; SMN2 | |
| SCHEMBL27454271 | 0.84 | BCHE (0.51) | KDM2BBCHE | |
| SCHEMBL14609068 | 0.84 | KDM2B (0.61) | KDM2BBCHESMN1; SMN2 | |
| SCHEMBL12155343 | 0.84 | BCHE (0.77) | KDM2BBCHE | |
| SCHEMBL12155272 | 0.83 | KDM2B (0.56) | KDM2BBCHESMN1; SMN2 | |
| Lithium Ion SCHEMBL10766583 | 0.83 | KDM2B (0.59) | KDM2BBCHE | |
| SCHEMBL21214043 | 0.82 | KDM2B (0.51) | KDM2BBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739067-A | NERVOUS SYSTEM, PSYCHOLOGICAL DISORDERS, HYPOTENSIVE AGENT, HORMONE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1988-04-19 | — | — | US | disclosed |
| EP-0234011-A1 | 4-(1,2,5,6-tetrahydro-1-alkyl-3-pyridinyl)-2-thiazolamines and 4-(hexahydro-1-alkyl-3-pyridinyl)-2-thiazolamines | WARNER-LAMBERT COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |
| US-4650805-A | 4-(1,2,5,6-Tetrahydro-1-alkyl-3-pyridinyl)-2-thiazolamines and 4-(hexahydro-1-alkyl-3-pyridinyl)-2-thiazolamines having anti-psychotic activity | WARNER-LAMBERT COMPANY (US) | 1987-03-17 | — | — | US | disclosed |