Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Beclamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7760563 | 0.84 | AOC3 (0.60) | GAAMEN1KMT2ACYP2C19ALDH1A1 | |
| Beclamide SCHEMBL35199 | 0.84 | GAA (0.72) | GAAMEN1KMT2ACYP3A4CYP2C19 | |
| Beclamide SCHEMBL7711127 | 0.82 | GAA (0.70) | GAAMEN1KMT2ACYP3A4CYP2C19 | |
| Beclamide SCHEMBL2444085 | 0.82 | GAA (0.70) | GAAMEN1KMT2ACYP3A4CYP2C19 | |
| Beclamide SCHEMBL5381439 | 0.82 | GAA (0.70) | GAAMEN1KMT2ACYP3A4CYP2C19 | |
| Beclamide SCHEMBL2312279 | 0.82 | GAA (0.70) | GAAMEN1KMT2ACYP3A4CYP2C19 | |
| Beclamide SCHEMBL6439067 | 0.82 | GAA (0.70) | GAAMEN1KMT2ACYP3A4CYP2C19 | |
| Beclamide SCHEMBL2943336 | 0.82 | GAA (0.70) | GAAMEN1KMT2ACYP3A4CYP2C19 | |
| Beclamide SCHEMBL7500450 | 0.81 | GAA (0.68) | GAAMEN1KMT2ACYP3A4CYP2C19 | |
| Beclamide SCHEMBL22686163 | 0.80 | GAA (0.62) | GAAMEN1KMT2ACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738803-A | ENZYME INHIBITORS | ROQUES BERNARD (FR) | 1988-04-19 | — | — | US | disclosed |
| US-4618708-A | ENKEPHALINASE INHIBITOR, ANALGESICS, ANTIDEPRESSANT, ANTIDIARRHEA, OR HYPOTENSIVE AGENT | ROQUES BERNARD (FR) | 1986-10-21 | — | — | US | disclosed |