SCHEMBL10692665

SCHEMBL10692665

CNCc1cccc2ccsc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.47
HTR2C P28335 2/20 0.47
DAO P14920 1/20 0.46
LTA4H P09960 1/20 0.45
IFNAR1 P17181 1/20 0.42
CYP2A6 P11509 3/20 0.42
HTR2B P41595 1/20 0.40
CYP19A1 P11511 2/20 0.37
XIAP P98170 1/20 0.36
OPRM1 P35372 1/20 0.36
OPRK1 P41145 1/20 0.36
ADRB2 P07550 2/20 0.36
PRMT6 Q96LA8 1/20 0.36
PIK3C2B O00750 1/20 0.35
HDAC4 P56524 1/20 0.35
LMNA P02545 1/20 0.35
RECQL P46063 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8504667 0.82 HTR2A (0.48) HTR2AHTR2CDAOCYP2A6HTR2B
SCHEMBL2610672 0.79 CYP2A6 (0.50) HTR2AHTR2CDAOCYP2A6CYP19A1
SCHEMBL3797459 0.76 DAO (0.43) HTR2AHTR2CDAOCYP2A6HTR2B
SCHEMBL30620284 0.75 DAO (0.49) HTR2AHTR2CDAOCYP2A6HTR2B
SCHEMBL113854 0.75 CYP2A6 (0.46) HTR2AHTR2CDAOLTA4HCYP2A6
SCHEMBL12432195 0.75 CYP2A6 (0.46) HTR2AHTR2CDAOCYP2A6HTR2B
SCHEMBL30620370 0.75 CYP2A6 (0.46) HTR2AHTR2CDAOCYP2A6HTR2B
SCHEMBL3154995 0.75 CYP2A6 (0.46) HTR2AHTR2CDAOCYP2A6HTR2B
SCHEMBL3056444 0.75 CYP2A6 (0.46) HTR2AHTR2CDAOCYP2A6HTR2B
SCHEMBL1281862 0.75 CYP2A6 (0.46) HTR2AHTR2CDAOCYP2A6HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4737516-A FUNGICIDES SANDOZ LTD. (CH) 1988-04-12 US disclosed
US-4542022-A FUNGICIDE SANDOZ LTD. (CH) 1985-09-17 US disclosed