SCHEMBL10692707

SCHEMBL10692707

CC(C)C(CC(=O)O)(C(=O)O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.58
HIF1A Q16665 1/20 0.58
CYP1A2 P05177 3/20 0.50
CYP2D6 P10635 3/20 0.50
KIF11 P52732 1/20 0.41
MIF P14174 1/20 0.39
MAPT P10636 3/20 0.37
KCNH2 Q12809 3/20 0.37
GRIN2D O15399 2/20 0.37
GRIN1 Q05586 2/20 0.37
GRIN2A Q12879 2/20 0.37
GRIN2B Q13224 2/20 0.37
GRIN2C Q14957 2/20 0.37
OPRM1 P35372 2/20 0.37
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
CACNA1F O60840 1/20 0.37
ABCB1 P08183 1/20 0.37
CYP2B6 P20813 1/20 0.37
DRD4 P21917 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10696236 0.84 CYP2C19 (0.49) CYP2C19HIF1ACYP1A2CYP2D6KIF11
SCHEMBL6758874 0.83 CYP2D6 (0.52) CYP2C19HIF1ACYP1A2CYP2D6KIF11
SCHEMBL3726388 0.83 CYP1A2 (0.52) CYP2C19HIF1ACYP1A2CYP2D6KIF11
SCHEMBL11786526 0.81 CYP1A2 (0.50) CYP2C19HIF1ACYP1A2CYP2D6KIF11
SCHEMBL29178235 0.77 CYP2C9 (0.45) CYP2C19HIF1ACYP1A2KIF11MAPT
SCHEMBL11421118 0.76 CYP1A2 (0.47) CYP2C19HIF1ACYP1A2CYP2D6KIF11
SCHEMBL1144334 0.74 CYP2C19 (0.58) CYP2C19HIF1ACYP1A2CYP2D6KIF11
SCHEMBL1144629 0.74 CYP2C19 (0.58) CYP2C19HIF1ACYP1A2CYP2D6KIF11
SCHEMBL27821483 0.74 CYP2D6 (0.46) CYP2C19HIF1ACYP1A2CYP2D6KIF11
SCHEMBL1604043 0.74 CYP2C19 (1.00) CYP2C19HIF1ACYP1A2CYP2D6KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110028403-B Method for synthesizing succinic acid compound 四川大学 2020-08-11 CN disclosed
CN-110028403-A A kind of method of synthesizing succinic acid class compound 四川大学 2019-07-19 CN disclosed
EP-0253501-A2 N-disubstituted cycloalkylmethyl amines useful as fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-01-20 EP disclosed