Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692925 | 1.00 | SPHK1 (0.40) | SPHK1RARBL3MBTL1TDP1MAPT | |
| SCHEMBL10692424 | 0.98 | SPHK1 (0.42) | SPHK1RARBMAPTRAB9ANPC1 | |
| SCHEMBL10692428 | 0.98 | SPHK1 (0.42) | SPHK1RARBMAPTRAB9ANPC1 | |
| SCHEMBL10716288 | 0.86 | SPHK1 (0.41) | SPHK1RARBL3MBTL1TDP1MAPT | |
| SCHEMBL10692937 | 0.86 | SPHK1 (0.41) | SPHK1RARBL3MBTL1TDP1MAPT | |
| SCHEMBL10692430 | 0.84 | SPHK1 (0.43) | SPHK1RARBMAPTRAB9ANPC1 | |
| SCHEMBL11076068 | 0.84 | SPHK1 (0.40) | SPHK1RARBL3MBTL1TDP1MAPT | |
| SCHEMBL11076070 | 0.84 | SPHK1 (0.40) | SPHK1RARBL3MBTL1TDP1MAPT | |
| SCHEMBL10356880 | 0.83 | MEN1 (0.41) | SPHK1RARBL3MBTL1TDP1MAPT | |
| SCHEMBL11066955 | 0.83 | SPHK1 (0.39) | SPHK1RARBL3MBTL1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4776973-A | LIQUID CRYSTAL ELECTROOPTICS DISPLAY DEVICE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-10-11 | — | — | US | disclosed |