Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 4/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.57 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.57 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481007 | 0.88 | CACNA1C (0.64) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL9674599 | 0.82 | CYP1A2 (0.76) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 | |
| SCHEMBL11814102 | 0.81 | CACNA1C (0.67) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 | |
| SCHEMBL9410990 | 0.81 | CACNA1C (0.62) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 | |
| SCHEMBL7431826 | 0.80 | CACNA1C (0.71) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10662554 | 0.80 | CACNA1C (0.52) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL11781966 | 0.79 | CACNA1C (0.67) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10743484 | 0.79 | CACNA1C (0.64) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10745321 | 0.78 | CACNA1C (0.62) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 | |
| SCHEMBL9173126 | 0.78 | CACNA1C (0.75) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4784958-A | CARDIOVASCULAR DISORDERS | GLOSSMANN HARTMUT (DE) | 1988-11-15 | — | — | US | disclosed |