SCHEMBL10693472

SCHEMBL10693472

CCCCCc1ccc(-c2ccc(-c3ccc(CCC)cc3)c(F)c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 11/20 0.63
RARA P10276 2/20 0.59
RARG P13631 1/20 0.59
HSD17B10 Q99714 3/20 0.46
TSHR P16473 1/20 0.46
HTR2A P28223 1/20 0.46
ALDH1A1 P00352 3/20 0.45
MEN1 O00255 2/20 0.45
MAPT P10636 2/20 0.45
KMT2A Q03164 2/20 0.45
MTOR P42345 1/20 0.45
HRH3 Q9Y5N1 1/20 0.43
ESR1 P03372 2/20 0.42
ADRA2A P08913 2/20 0.42
ADORA3 P0DMS8 2/20 0.42
TACR2 P21452 2/20 0.42
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
KDM4E B2RXH2 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9510907 1.00 RARB (0.63) RARBRARARARGHSD17B10TSHR
SCHEMBL9513819 0.98 RARB (0.65) RARBRARARARGHSD17B10TSHR
SCHEMBL9563758 0.98 RARB (0.65) RARBRARARARGHSD17B10TSHR
SCHEMBL13111984 0.98 RARB (0.64) RARBRARARARGHSD17B10TSHR
SCHEMBL14175167 0.97 RARB (0.66) RARBRARARARGHSD17B10TSHR
SCHEMBL17359399 0.95 RARB (0.57) RARBRARARARGHSD17B10TSHR
SCHEMBL14175166 0.95 RARB (0.64) RARBRARARARGHSD17B10TSHR
SCHEMBL9563730 0.95 RARB (0.68) RARBRARARARGHSD17B10TSHR
SCHEMBL13310852 0.95 RARB (0.68) RARBRARARARGHSD17B10TSHR
SCHEMBL14175164 0.95 RARB (0.64) RARBRARARARGHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024665-B2 Polymer-stabilized liquid crystal composition and use thereof BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2024-07-02 US disclosed
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
EP-2808375-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT PRODUCED USING SAME DAINIPPON INK & CHEMICALS (JP) 2020-01-22 EP disclosed
US-20180187079-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2018-07-05 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-9938463-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2018-04-10 US disclosed
EP-2735600-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DAINIPPON INK & CHEMICALS (JP) 2018-01-17 EP disclosed
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 EP disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
US-8029696-B2 Fused naphthalenes MERCK PATENT GMBH (DE) 2011-10-04 US disclosed
US-20100059711-A1 FUSED NAPHTHALENES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-03-11 US disclosed
WO-2008012180-A9 FUSED NAPHTHALENES MERCK PATENT GMBH (DE) 2009-03-19 WO disclosed
US-7390538-B2 Liquid-crystal medium containing monofluoroterphenyl compounds MERCK PATENT GMBH (DE) 2008-06-24 US disclosed
WO-2008012180-A1 FUSED NAPHTHALENES MERCK PATENT GMBH (DE) 2008-01-31 WO disclosed
US-20070001149-A1 Liquid-crystal medium containing monofluoroterphenyl compounds MERCK PATENT GMBH (DE) 2007-01-04 US disclosed
EP-0132377-B1 COMPOUNDS CONTAINING A FLUOROBIPHENYLYL GROUP AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICE The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1988-06-29 EP disclosed
US-4696549-A Compounds containing a fluorobiphenylyl group and their use in liquid crystal material and devices THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1987-09-29 US disclosed
US-4594465-A Compounds containing a fluorobiphenylyl group THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1986-06-10 US disclosed
EP-0132377-A2 Compounds containing a fluorobiphenylyl group and their use in liquid crystal materials and device The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1985-01-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 RARB 3196/4885RARA 3675/4885RARG 3904/4885
US-20100059711-A1 FUSED NAPHTHALENES CCNE2, CCNE1, F12 RARB 2984/4885RARA 2546/4885RARG 2202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.