SCHEMBL10693750

SCHEMBL10693750

O=C1NC(=O)C2(c3ccc(Cl)c(Cl)c3)CCCCC12

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 20/20 0.46
SLC6A3 Q01959 20/20 0.46
SLC6A2 P23975 12/20 0.46
CYP2D6 P10635 6/20 0.46
KCNH2 Q12809 6/20 0.46
CYP3A4 P08684 5/20 0.46
CYP1A1 P04798 5/20 0.46
CYP1A2 P05177 5/20 0.46
CYP2C19 P33261 3/20 0.42
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3984947 0.82 CYP19A1 (0.59) SLC6A4SLC6A3SLC6A2CYP2D6KCNH2
SCHEMBL2494534 0.78 SLC6A4 (0.53) SLC6A4SLC6A3SLC6A2CYP2D6KCNH2
SCHEMBL13272960 0.78 SLC6A4 (0.53) SLC6A4SLC6A3SLC6A2CYP2D6KCNH2
SCHEMBL20203032 0.78 SLC6A4 (0.53) SLC6A4SLC6A3SLC6A2CYP2D6KCNH2
SCHEMBL11862081 0.77 CYP19A1 (0.45)
SCHEMBL22966075 0.76 CYP19A1 (0.44)
SCHEMBL2469280 0.72 SLC6A4 (0.47) SLC6A4SLC6A3SLC6A2CYP2D6KCNH2
SCHEMBL20210205 0.72 SLC6A4 (0.47) SLC6A4SLC6A3SLC6A2CYP2D6KCNH2
SCHEMBL13272953 0.72 SLC6A4 (0.47) SLC6A4SLC6A3SLC6A2CYP2D6KCNH2
SCHEMBL20203033 0.72 SLC6A4 (0.47) SLC6A4SLC6A3SLC6A2CYP2D6KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0266662-A2 Process for the preparation of poly(arylensulphides) with lower crystallization temperature BAYER AG (DE) 1988-05-11 EP disclosed