Hydroxyamine

Hydroxyamine

SCHEMBL10693793

CCCCC(CC)COC(=O)CC.CCCCC(CC)COC(=O)CC.NO

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.72
TSHR P16473 3/20 0.72
TDP1 Q9NUW8 3/20 0.72
ATM Q13315 1/20 0.72
RECQL P46063 1/20 0.59
ALDH1A1 P00352 7/20 0.54
CA2 P00918 3/20 0.54
LMNA P02545 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
MAPK1 P28482 3/20 0.48
HSD17B10 Q99714 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
NAAA Q02083 1/20 0.44
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP14 P50281 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1155390 0.96 CYP3A4 (0.77) CYP3A4TSHRTDP1ATMRECQL
Propionic Acid SCHEMBL28575585 0.91 CYP3A4 (0.70) CYP3A4TSHRTDP1ATMRECQL
Propionic Acid SCHEMBL29203862 0.90 CYP3A4 (0.68) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL28665169 0.89 CYP3A4 (0.67) CYP3A4TSHRTDP1ATMRECQL
Propionic Acid SCHEMBL29203861 0.88 CYP3A4 (0.66) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL544230 0.87 CYP3A4 (0.74) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL4581930 0.86 CYP3A4 (0.72) CYP3A4TSHRTDP1ATMRECQL
Acrylic Acid SCHEMBL27940462 0.85 TSHR (0.68) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL2215691 0.85 CYP3A4 (0.77) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL44320 0.85 CYP3A4 (0.89) CYP3A4TSHRTDP1ATMRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0269570-A2 Compositions stabilized with N-hydroxyiminodiacetic or dipropionic acids or esters thereof CIBA-GEIGY AG (CH) 1988-06-01 EP disclosed