Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10757925 | 0.97 | SMPD1 (0.50) | SMPD1KDM4EABCB1MAPTHCN4 | |
| Oxalic Acid SCHEMBL10694123 | 0.93 | SMPD1 (0.48) | SMPD1KDM4EALDH1A1ABCB1SIGMAR1 | |
| Oxalic Acid SCHEMBL10688530 | 0.90 | SMPD1 (0.45) | SMPD1KDM4EALDH1A1ABCB1SIGMAR1 | |
| SCHEMBL10754672 | 0.89 | SMPD1 (0.51) | SMPD1ABCB1MAPTHCN4 | |
| Hydrochloric Acid SCHEMBL10693968 | 0.84 | SMPD1 (0.52) | SMPD1ABCB1MAPTHCN4 | |
| Hydrochloric Acid SCHEMBL10369261 | 0.82 | SMPD1 (0.48) | SMPD1KDM4EABCB1SIGMAR1MAPT | |
| SCHEMBL10410304 | 0.82 | SMPD1 (0.52) | SMPD1KDM4EABCB1MAPTHCN4 | |
| SCHEMBL10695992 | 0.78 | SCN9A (0.39) | KDM4EALDH1A1L3MBTL1MAPT | |
| Oxalic Acid SCHEMBL10721387 | 0.77 | SMPD1 (0.48) | SMPD1KDM4EALDH1A1ABCB1 | |
| Hydrochloric Acid SCHEMBL10369431 | 0.77 | SMPD1 (0.49) | SMPD1KDM4EABCB1MAPTHCN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778793-A | CONTROLLING CALCIUM CONCENTRATION-CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |