Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | ACHE | P22303 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4818250 | 0.87 | TP53 (0.67) | MAOBSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL11396751 | 0.80 | MAOB (0.71) | MAOBSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL28682651 | 0.79 | MAOB (0.70) | MAOBSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL28563825 | 0.79 | SMN1; SMN2 (0.74) | MAOBSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL893303 | 0.78 | KDM4E (1.00) | MAOBSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL17664186 | 0.77 | MAOB (0.68) | MAOBSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL28650599 | 0.77 | MEN1 (0.66) | MAOBSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL11391879 | 0.75 | SMN1; SMN2 (0.73) | MAOBSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL3046337 | 0.75 | MAOB (0.61) | MAOBSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL15744626 | 0.75 | P2RY14 (0.82) | SMN1; SMN2NPC1RAB9APKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4777269-A | 7-Phenylacetic acid-4-alkyl-coumarinyl amides useful in fluorometric determination of the activity of hydrolases | EUROPEAN ATOMIC ENERGY COMMUNITY (LU) | 1988-10-11 | — | — | US | disclosed |