Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | STAT5A | P42229 | 1/20 | 0.47 |
| ▸ | STAT5B | P51692 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24892110 | 0.93 | KMT2A (0.56) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL30180871 | 0.89 | KMT2A (0.63) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL10696567 | 0.86 | MEN1 (0.50) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL10644987 | 0.86 | NAMPT (0.58) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL19639325 | 0.86 | MEN1 (0.57) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL10695067 | 0.85 | NAMPT (0.60) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL10693788 | 0.85 | NAMPT (0.60) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL10606782 | 0.84 | F2 (0.57) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL24892111 | 0.84 | KMT2A (0.48) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL10694927 | 0.84 | TRPV1 (0.52) | KMT2AMEN1NPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268267-A2 | Guanidinomethylbenzoic acid derivatives, compositions containing the same, processes for preparing the same, and the use of the same in the manufacture of medicaments of therapeutic value | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1988-05-25 | — | — | EP | disclosed |