Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | DTYMK | P23919 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077316 | 1.00 | CYP1A2 (0.69) | CYP1A2PDK1SNCAMAOAMAOB | |
| SCHEMBL29764342 | 0.85 | CYP1A2 (0.50) | CYP1A2PDK1SNCAMAOAMAOB | |
| SCHEMBL865986 | 0.81 | CYP1A2 (1.00) | CYP1A2ALDH1A1 | |
| SCHEMBL3291900 | 0.81 | CYP1A2 (1.00) | CYP1A2ALDH1A1 | |
| SCHEMBL15272523 | 0.81 | CYP1A2 (0.71) | CYP1A2PDK1SNCAMAOAMAOB | |
| SCHEMBL888064 | 0.81 | CYP1A2 (0.44) | CYP1A2PDK1SNCAPARP1ALDH1A1 | |
| SCHEMBL9452749 | 0.80 | CYP1A2 (0.69) | CYP1A2PDK1NPC1RAB9AL3MBTL1 | |
| SCHEMBL442788 | 0.80 | CYP1A2 (0.69) | CYP1A2PDK1NPC1RAB9AL3MBTL1 | |
| SCHEMBL1492461 | 0.80 | CYP1A2 (0.69) | CYP1A2PDK1MAOAMAOBNPC1 | |
| SCHEMBL1224216 | 0.80 | CYP1A2 (0.69) | CYP1A2PDK1SNCAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267996-A1 | New nucleotide derivatives | TAMIR BIOTECHNOLOGY LTD. (IL) | 1988-05-25 | — | — | EP | disclosed |
| US-4426536-A | Synthesis of phenylacetic acid esters | ELI LILLY AND COMPANY (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0098058-A1 | Synthesis of phenylacetic acid esters | ELI LILLY AND COMPANY (US) | 1984-01-11 | — | — | EP | disclosed |