SCHEMBL10695524

SCHEMBL10695524

CN(CCC(=N)N)C(=O)c1cc(N(C)C(=O)c2cc(NC(=O)N(CCCl)N=O)c[nH]2)c[nH]1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.33
EGFR P00533 3/20 0.32
ERBB2 P04626 3/20 0.32
HRAS P01112 2/20 0.30
ESR1 P03372 2/20 0.30
ESR2 Q92731 2/20 0.30
MEN1 O00255 1/20 0.30
ABCB11 O95342 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GSR P00390 1/20 0.30
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10691326 0.99 DAO (0.33) DAOEGFRERBB2HRASESR1
SCHEMBL10690297 0.88 DAO (0.37) DAO
Hydrochloric Acid SCHEMBL10693757 0.87 DAO (0.37) DAO
SCHEMBL10693697 0.86 DAO (0.34) DAOEGFRERBB2MEN1ABCB11
SCHEMBL10695100 0.86 DAO (0.34) DAOEGFRERBB2MEN1ABCB11
Hydrochloric Acid SCHEMBL10687743 0.86 DAO (0.34) DAOEGFRERBB2MEN1ABCB11
Hydrochloric Acid SCHEMBL10694105 0.86 DAO (0.34) DAOEGFRERBB2MEN1ABCB11
SCHEMBL10693599 0.85 DAO (0.36) DAOHRASESR1ESR2
Hydrochloric Acid SCHEMBL10693303 0.84 DAO (0.35) DAOHRASESR1ESR2
SCHEMBL9527804 0.81 DAO (0.35) DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4766142-A ANTICARCINOGENIC AGENTS FARMITALIA CARLO ERBA S.R.L. (IT) 1988-08-23 US disclosed