Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27275924 | 0.76 | POLB (0.60) | POLBALDH1A1TSHRCYP2D6SMN1; SMN2 | |
| SCHEMBL10365830 | 0.75 | POLB (0.60) | POLBALDH1A1TSHRCYP2D6CYP1A2 | |
| SCHEMBL11548674 | 0.74 | KDM4E (0.46) | ALDH1A1SMN1; SMN2CYP1A2OPRM1OPRD1 | |
| SCHEMBL13866493 | 0.72 | POLB (0.81) | POLBALDH1A1TSHRCYP2D6CYP1A2 | |
| SCHEMBL6027881 | 0.72 | POLB (0.81) | POLBALDH1A1TSHRCYP2D6CYP1A2 | |
| SCHEMBL6322387 | 0.72 | POLB (0.53) | POLBALDH1A1TSHRCYP2D6SMN1; SMN2 | |
| SCHEMBL6319539 | 0.72 | POLB (0.53) | POLBALDH1A1TSHRCYP2D6SMN1; SMN2 | |
| SCHEMBL10385466 | 0.71 | POLB (0.65) | POLBALDH1A1TSHRCYP2D6CYP1A2 | |
| SCHEMBL6320349 | 0.71 | POLB (0.49) | POLBALDH1A1TSHRCYP2D6SMN1; SMN2 | |
| SCHEMBL6320347 | 0.71 | POLB (0.49) | POLBALDH1A1TSHRCYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254532-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-27 | — | — | EP | disclosed |