Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | APEX1 | P27695 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10696509 | 0.95 | KMT2A (0.54) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| Bromide SCHEMBL10695912 | 0.90 | KMT2A (0.49) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| SCHEMBL10528959 | 0.89 | NR1I2 (0.56) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| Bromide SCHEMBL10694969 | 0.88 | KMT2A (0.47) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| SCHEMBL10695812 | 0.87 | TDP1 (0.50) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| Iodide SCHEMBL10695810 | 0.86 | KMT2A (0.56) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| SCHEMBL9526890 | 0.85 | TDP1 (0.61) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| Iodide SCHEMBL10695908 | 0.85 | KMT2A (0.55) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| SCHEMBL11320269 | 0.84 | NR1I2 (0.56) | TDP1MAPTHSD17B10APEX1ALDH1A1 | |
| Iodide SCHEMBL10690864 | 0.82 | KMT2A (0.49) | TDP1MAPTHSD17B10APEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785090-A | ANTIBIOTICS, BACTERICIDES | MEIJI SEIKA KAISHA, LTD. (JP) | 1988-11-15 | — | — | US | disclosed |