⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17079759 | 1.00 | — | — | |
| SCHEMBL10697182 | 1.00 | — | — | |
| SCHEMBL10486910 | 0.72 | — | — | |
| SCHEMBL10486907 | 0.72 | — | — | |
| SCHEMBL14243820 | 0.71 | — | — | |
| SCHEMBL16431826 | 0.71 | — | — | |
| SCHEMBL3941328 | 0.71 | — | — | |
| SCHEMBL9955471 | 0.71 | — | — | |
| SCHEMBL4697882 | 0.71 | — | — | |
| SCHEMBL7761227 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720543-A | 1a-7-substituted derivatives of mitomycin and uses thereof | GEORGETOWN UNIVERSITY (US) | 1988-01-19 | — | — | US | disclosed |
| EP-0222901-A1 | 1a-7-SUBSTITUTED DERIVATIVES OF MITOMYCIN AND USES THEREOF | GEORGETOWN UNIVERSITY (US) | 1987-05-27 | — | — | EP | disclosed |
| WO-1986007260-A1 | 1a-7-SUBSTITUTED DERIVATIVES OF MITOMYCIN AND USES THEREOF | GEORGETOWN UNIVERSITY (US) | 1986-12-18 | — | — | WO | disclosed |