Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640394 | 0.89 | FUCA1 (0.56) | FUCA1GBA1RORCSIGMAR1S1PR1 | |
| SCHEMBL4640399 | 0.89 | FUCA1 (0.56) | FUCA1GBA1RORCSIGMAR1S1PR1 | |
| SCHEMBL4640392 | 0.89 | FUCA1 (0.56) | FUCA1GBA1RORCSIGMAR1S1PR1 | |
| SCHEMBL500305 | 0.81 | GBA1 (0.49) | FUCA1GBA1RORCSIGMAR1S1PR1 | |
| SCHEMBL500304 | 0.81 | GBA1 (0.49) | FUCA1GBA1RORCSIGMAR1S1PR1 | |
| SCHEMBL500306 | 0.81 | GBA1 (0.49) | FUCA1GBA1RORCSIGMAR1S1PR1 | |
| SCHEMBL500415 | 0.81 | GBA1 (0.49) | FUCA1GBA1RORCSIGMAR1S1PR1 | |
| SCHEMBL4503332 | 0.81 | GBA1 (0.49) | FUCA1GBA1RORCSIGMAR1S1PR1 | |
| SCHEMBL13382323 | 0.81 | GBA1 (0.65) | FUCA1GBA1RORCSIGMAR1S1PR1 | |
| SCHEMBL4506217 | 0.81 | GBA1 (0.49) | FUCA1GBA1RORCSIGMAR1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4786649-A | ANTISEPTICS | OTSUKA PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-11-22 | — | — | US | disclosed |
| EP-0228035-A2 | Antimicrobial 1-thienyl-4-oxoquinoline-3-carboxylix acid compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-07-08 | — | — | EP | disclosed |