Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17426060 | 0.83 | EHMT2 (0.51) | TSHRCYP3A4CYP2C19CAPN1EHMT2 | |
| SCHEMBL289305 | 0.81 | CAPN1 (0.60) | TSHRCYP3A4CYP2C19CAPN1MEN1 | |
| SCHEMBL289304 | 0.81 | CAPN1 (0.60) | TSHRCYP3A4CYP2C19CAPN1MEN1 | |
| SCHEMBL28021324 | 0.79 | CAPN1 (0.64) | TSHRCYP3A4CYP2C19CAPN1MEN1 | |
| SCHEMBL19290951 | 0.77 | TSHR (0.51) | TSHRCYP3A4CYP2C19CAPN1MEN1 | |
| SCHEMBL23564393 | 0.76 | TSHR (0.54) | TSHRCYP3A4CYP2C19CAPN1MEN1 | |
| SCHEMBL23564389 | 0.76 | TSHR (0.54) | TSHRCYP3A4CYP2C19CAPN1MEN1 | |
| SCHEMBL23563775 | 0.76 | TSHR (0.54) | TSHRCYP3A4CYP2C19CAPN1MEN1 | |
| SCHEMBL23564233 | 0.76 | TSHR (0.54) | TSHRCYP3A4CYP2C19CAPN1MEN1 | |
| SCHEMBL13262070 | 0.74 | MEN1 (0.45) | TSHRCYP3A4CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266563-A2 | Use of 1-benzyl-amino-alkyl-pyrrolidinones as antidepressants | BOEHRINGER INGELHEIM KG (DE) | 1988-05-11 | — | — | EP | disclosed |