Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9285763 | 1.00 | MAPT (0.46) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL8527292 | 0.91 | MAPT (0.46) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL6051390 | 0.91 | MAPT (0.46) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL6051393 | 0.91 | MAPT (0.46) | MAPTKMT2AMEN1GAANPSR1 | |
| Hydrochloric Acid SCHEMBL10696662 | 0.91 | MAPT (0.46) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL11305480 | 0.89 | KMT2A (0.46) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL11305476 | 0.89 | KMT2A (0.44) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL11305477 | 0.89 | KMT2A (0.44) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL9345522 | 0.88 | KMT2A (0.55) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL9345517 | 0.88 | KMT2A (0.55) | MAPTKMT2AMEN1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272827-A2 | 3-Heterocyclicthiomethyl cephalosphorins | ZENECA Pharma S.A. (FR) | 1988-06-29 | — | — | EP | disclosed |