Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.68 |
| ▸ | HTR2B | P41595 | 2/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.64 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696871 | 1.00 | HTR2C (0.68) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13742286 | 0.82 | HTR2C (0.97) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10694369 | 0.82 | HTR2C (0.68) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10698042 | 0.82 | HTR2C (0.68) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL4134455 | 0.81 | HTR2C (1.00) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL4134458 | 0.81 | HTR2C (1.00) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13751924 | 0.79 | SLC6A4 (0.74) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14568542 | 0.78 | SLC6A4 (1.00) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3614757 | 0.77 | HTR2C (0.63) | HTR2CHTR2BSLC6A2SLC6A3KDM1A | |
| SCHEMBL16388354 | 0.77 | HTR2C (0.63) | HTR2CHTR2BSLC6A2SLC6A3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253498-A2 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-20 | — | — | EP | disclosed |